Regulatory validation Archives - ECETOC

Publications

Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

378217

2024-03-04 08:39:37 read more

Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)

Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)

378213

2024-02-08 15:53:50 read more

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology

378204

2023-10-19 07:44:34 read more

Heterogeneity in biological assemblages and exposure in chemical risk assessment: Exploring capabilities and challenges in methodology with two landscape-scale case studies

Heterogeneity in biological assemblages and exposure in chemical risk assessment: Exploring capabilities and challenges in methodology with two landscape-scale case studies

378168

2022-10-18 13:15:06 read more

Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro‑to‑in vivo extrapolation (IVIVE) in chemical risk assessment

Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro‑to‑in vivo extrapolation (IVIVE) in chemical risk assessment

378165

2022-09-29 07:00:30 read more

Recommendations on dose level selection for repeat dose toxicity studies

Recommendations on dose level selection for repeat dose toxicity studies

378197

2022-04-29 11:53:44 read more

A framework for chemical safety assessment incorporating new approach methodologies within REACH

A framework for chemical safety assessment incorporating new approach methodologies within REACH

378148

2022-02-23 07:39:58 read more

Creating sets of similar nanoforms with the ECETOC NanoApp: real-life case studies

Creating sets of similar nanoforms with the ECETOC NanoApp: real-life case studies

378133

2021-07-13 06:01:28 read more

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?

378132

2021-06-09 04:30:32 read more

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Task Forces

Staged assessment: Exemplify the staged assessment process by using it to provide more information in low tonnage bands

Staged assessment: Exemplify the staged assessment process by using it to provide more information in low tonnage bands

387802

2023-02-17 13:21:27 387802

Smart studies: Examine how in vivo studies could provide more information encompassing novel studies (and endpoints)

Smart studies: Examine how in vivo studies could provide more information encompassing novel studies (and endpoints)

387801

2023-02-17 13:12:35 387801

Use of clinical data in identification of respiratory sensitisers

Use of clinical data in identification of respiratory sensitisers

387799

2022-04-04 08:18:48 387799

Dose Selection Task Force

Dose Selection Task Force

387793

2019-06-13 13:42:29 387793

View all completed task forces